The diagnosis is based on clinical criteria, biochemical assays and gene analyses. Patients with easy bruising should be evaluated for bleeding disorders.
- In mild forms, patients can learn to reduce dislocations by limiting physical activity.
- In severe cases, surgical repair and tightening of joint ligaments can be undertaken; however majority ligaments in these patients do not hold sutures well.
- Surgical repair of aneurysm.
Women with Type IV EDS should be counseled about the increased risk of uterine rupture, bleeding, and other complications of pregnancy.