Acute febrile neutrophilic dermatosis (Sweet's syndrome) is rare but not unusual. Most are idiopathic or associated with benign diseases. It is commonly seen in women between 30-50 years. Sweet's syndrome in children is very rare and usually associated with infection. Female-male ratio is of 15:1.
Most cases of Sweet's syndrome resolve, although some may persist indefinitely and can be difficult to manage because of the pain and skin lesions. Since this condition may be associated with many other diseases, including malignant tumors, the overall prognosis of the patient depends on the underlying cause.